Recommended Builds and Tactics

Minion/Witch Builds: Summons can pressure Siora while you focus on Path of Exile 2 Currency dodging, but limited arena space makes it harder to stay safe. Positioning is critical.
Bow/Ranged Builds: Strong for this fight since you can maintain distance and react to mechanics, but careful stamina/mana management is needed for constant dodging.
Melee Builds: More dangerous due to scythe spins and lightning lines, but Lifetap or leech-heavy builds can muscle through if you burst her down quickly.

Tip: Flasks that restore life instantly and movement speed buffs are lifesavers here.

Rewards for Defeating Siora

After Siora falls, Una will arrive to continue the Ezomyte recruitment questline. While she doesn't drop unique loot every time, defeating her progresses the story and grants valuable mid-game gear and currency.

Possible rewards include:

Rare equipment with lightning-related modifiers
Progression unlocks for the Ezomytes
Currency shards and crafting Path of Exile 2 Items

Final Thoughts

Siora, Blade of the Mists, is a mid-game boss that tests your ability to stay mobile and react under pressure in Path of Exile 2. While her mechanics aren't overly complex, the tight arena combined with constant lightning damage makes the fight punishing for careless players.

To succeed:

Max out lightning resistance.
Prioritize mobility.
React fast to the dark mist phase.

Once you bring her down, you'll be one step closer to buy POE 2 Chaos Orbs securing the Ezomytes' support and advancing deeper into the Interludes of Path of Exile 2.